The 7 Best 12 Hour Allergy medicines (2023 reviews)

We consider a 12 hour allergy medicine to be a worthy investment in the long run. We are here to help you choose the right one for your purposes from all the best available products in market today.

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Our Top Picks:

Best Overall: Buy: Claritin 12 Hour Allergy Medicine READ REVIEW

Best For NIGHTTIME: Buy: Xyzal 12 Hour Allergy Medicine READ REVIEW

Best For dog: Buy: Allegra 12 Hour Allergy Medicine READ REVIEW

Best For OUTDOOR Allergy: Buy: Healthcareaisle 12 Hour Allergy Medicine READ REVIEW

Best For Non drowsy: Buy: Basic Care 12 Hour Allergy Medicine READ REVIEW

Best For coughing: Buy: Allegra Hour Relief READ REVIEW

Best For Seasonal Allergy: Buy: Astepro 12 Hour Allergy Medicine READ REVIEW

Best Overall: Claritin 12 Hour Allergy Medicine

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The claritin 12 hour allergy medicine is specially designed for your daily purpose and has plenty of most useful features. It's bad enough to have alligators in your pool, rattlesnakes and coral snakes in your yard, and fire ants and scorpions just about everywhere. It really does help and this size is much more economical than buying single or a few doses at a time. Take one tablet a day of this 24 hour Claritin is extremely helpful in mediating the effects of all these allergens and is also very cost effective. It does not keep you up at night.

The added benefit this medication has is that it does not cause somnolence. It is great to have on hand during the spring. The pills are very tiny too, so if you're sensitive to pill size they should be ideal.

• Great allergy tablets and best value
• Most effective, tiny but mighty, non-drowsy allergy pill
• New and hot release

Best For NIGHTTIME: Xyzal 12 Hour Allergy Medicine

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The xyzal 12 hour allergy medicine should be able to handle its purpose and duties with ease. It’s the most effective otc antihistamine out there. It provides continuous allergy relief that is just as effective at hour 24 as it is at hour. The Xyzal is taken at night before going to bed so you wake feeling refreshed and symptom-free in the morning when pollen is at its worst. They will make you sleepy like Benadryl. It works effectively for at least 24 hours. Your itch will be cured if you clean your genital area daily. This is a great allergy medicine. It’s a great replacement for Zyrtec or Allegra.

• Good for allergies, if it works for you
• Sleepy side effects, works as well as benadryl
• One of the new comers and featured product

Best For dog: Allegra 12 Hour Allergy Medicine

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Allegra line of medicine come in a pretty wide variety of styles, so you can definitely find one that suits your individual preferences and needs. Allegra allergy medicine won’t cause drowsiness, so you don’t have to worry about feeling tired after you take it. It works on Allergies. Allegra tablets start working in one hour to give you round-the-clock relief from sneezing, runny nose, itchy and watery eyes, and itchy nose or throat. It reduces a nasal drip and prevents sneezing and other allergic symptoms. It is indicated for the temporary relief of symptoms due to upper respiratory allergies or hay fever, which can be caused by an allergic response to indoor or outdoor allergens.

• Helps control allergy symptoms year round
• 24 hour relief is awesome and homely
• Great over night travel game changers

Best For OUTDOOR Allergy: Healthcareaisle 12 Hour Allergy Medicine

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Best part: healthcareaisle 12 hour allergy medicine costs comparatively low and it is available to ship in 24 hours. Fexofenadine tablets provide 12 hours of allergy relief. It is a non-drowsy allergy medicine that provides effective relief from indoor and outdoor allergies. It has the same active ingredient as allegra allergy 24 hour tablets. It can be used as directed for allergy relief so you can get on with your day.

• New and hot release
• One of the new comers and featured product

Best For Non drowsy: Basic Care 12 Hour Allergy Medicine

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The features department is where basic care 12 hour allergy medicine truly manages to shine. It comes with allergy relief from Amazon basic care loratadine tablets 10 mg, you will once again be the boss of spring. The Basic Care Allergy Relief Loratadine works as intended in providing indoor and outdoor relief. The active ingredient is loratadine 10 mg, an antihistamine with original prescription strength that won’t make you drowsy when taken as directed. The tablets offer a non drowsy formula that provides 24 hour relief from symptoms including sneezing, runny nose, itchy or watery eyes, and itchy throat or nose.

These tablets definitely last for 24 hours. It provides all day, 24 hour relief of sneezing, runny nose, itchy, watery eyes, and itchy throat or nose. The tablets are small and easy to swallow.

• Great value compared to regular chain stores
• Lot of satisfied buyers

Best For coughing: Allegra Hour Relief

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The allegra hour relief is capable of outshining several other medicine featured in this list in overall features for the price point. Allegra allergy medicine won’t cause drowsiness, so you don’t have to worry about feeling tired after you take it. Allegra tablets start working in one hour to give you relief from your worst allergy symptoms, such as sneezing, runny nose, itchy and watery eyes, and itchy nose or throat. This product gets to work fast without knocking you over the head. It is indicated for the temporary relief of symptoms due to upper respiratory allergies or hay fever, which can be caused by an allergic response to indoor or outdoor allergens.

It's a wonderful item because it does what it says it's supposed to do no runny nose or no drowsiness. These are smaller in size than the 24 hr tabs.

• Works like magic for the seasonal allergies
• Helps stop sneezing and running nose
• Works really well to prevent and keep hives at bay

Best For Seasonal Allergy: Astepro 12 Hour Allergy Medicine

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The astepro 12 hour allergy medicine is suitable and reliable and fits well with your regular usage. This Astepro Allergy, Steroid Free antihistamine nasal spray is great. It is the first and only 24 hour, steroid-free nasal spray for allergy relief. The pump administers a fine mist of medicine at the correct dose every time. It does have an after taste that lingers after using. It works well for indoor allergies. The expiration date is clearly labeled and the instructions are clear. This spray has the benefit of being steroid free and works more quickly.

• Works for almost a whole day
• Excellent nose spray if you have seasonal allergies
• Works as well as the prescription azelastine