The 6 Best Natural Enzyme sprays (2023 reviews)

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Are you looking for collection of best natural enzyme sprays ? This page is just for you.

Our review process:

Our Top Picks:

Best Overall:
Buy: Rocco Roxie supply co Cleaning Solution
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Best For Dog poop Smell:
Buy: Furryfreshness Natural Enzyme Spray
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Best For Stain Removal:
Buy: Rocco Roxie supply co Natural Enzyme Spray
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Best For woes Of Puppy house training:
Buy: Natures Miracle Pet Stain
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Best For grass:
Buy: Petsafe Natural Enzyme Spray
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Best For cleanup:
Buy: Natures Miracle Natural Enzyme Spray
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Best Overall: Rocco Roxie supply co Cleaning Solution

Rocco Roxie supply co Cleaning Solution
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We know from years of feedback from readers, customers and amazon sellers, what most people want in a spray. The rocco roxie supply co cleaning solution is exactly that - it's a simple spray that hits all the right notes. This is the ONLY enzyme cleaner that actually removes cat urine smell for humans and other cats. It will take odors out and the solution itself does not smell pleasant. The smell of the product isn't full of perfume, it is fresh and clean. It is a bit heavy of a scent. The minty smell is also a nice cover and does dissipate over a day.

This stuff is the best and the smell takes away the other gross smells without having that chemical residue and smell lingering. It is great to clean up after any organic mess.

Why We Like This:
  • Worked great to remove puppy pee accidents
  • Works great and does not have much of a chemical smell
  • Best product for removing dog stains and smells
  • Gets rid of poo / pee smell instantly for wood floors

Best For Dog poop Smell: Furryfreshness Natural Enzyme Spray

Furryfreshness Natural Enzyme Spray
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The furryfreshness natural enzyme spray should be able to handle its purpose and duties with ease. This product will remove anything that comes from a pet. Not only does it work on new stains easily, it also eliminates some really old nasty stains too. It works great, no scents or stains left behind. This removes the odor as well as the stain. It's also the easiest one to use, because if it is a urine stain you just spray it until it's saturated and you're done.

This stuff works well on stains and it is great with no scrubbing. It's done a remarkable job in treating odor that managed to persist through Nature's Miracle and several pet-formula carpet shampoos.

Why We Like This:
  • Very best pet stain & odor eliminator ever
  • Just "odorless" once the pet urine smell is gone
  • Disappears from the white rug almost instantly

Best For Stain Removal: Rocco Roxie supply co Natural Enzyme Spray

Rocco Roxie supply co Natural Enzyme Spray
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Best part: rocco roxie supply co natural enzyme spray costs comparatively low and it is available to ship in 24 hours. It has more of an industrial-type smell rather than flowery but it is not over-powering or unpleasant. It can be used on animals or given to animals to drink. It is good for removing dog urine spots and stains. It’s almost a cinnamon chemical smell and it is STRONG. The smell is pleasant and dissipates over time. It will remove the stain but it might remove most of the odor. It's in a spray bottle, and there are no instructions for using it with a rug-cleaning machine. It is great for removing dog urine spots and stains.

Why We Like This:
  • Smells awful but gets pee smell out
  • Smells great and once dry, the urine smell is gone and doesn't come back
  • Great for upholstery and carpet alike

Best For woes Of Puppy house training: Natures Miracle Pet Stain

Natures Miracle Pet Stain
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The natures miracle miracle pet stain is satisfactory and appropriate and fits well with your regular usage. The trusted enzymatic formula works to eliminate the toughest pet stain and odor messes, leaving you with a fresh, clean home. The urine destroyer is made specifically for urine messes. It smells fresh and clean, so if you have a smelly mess to address, this version offers several advantages.

It is an excellent carpet treatment for cat urine. The advanced formula is meant for the most severe messes not just urine. It is great for odor elimination, not so great for long-term stain removal. These wipes can also be used to keep pets clean and fresh in between baths or on pets that are difficult to bathe. It will work on fresh urine stains not just urine.

Why We Like This:
  • Works excellent on cat pee spots if you follow the instructions
  • Great product for removing the yellow stains on a white carpet
  • Has a nice clean smell and cleaned everything up without problems

Best For grass: Petsafe Natural Enzyme Spray

Petsafe Natural Enzyme Spray
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The petsafe natural enzyme spray is suitable and reliable and fits well with your daily purpose. The Piddle Pad is the best invention ever. The PetSafe piddle place bio+ turf treatment spray naturally and safely uses enzymes to break down proteins in your pet’s waste to eliminate odors. The light lemongrass and eucalyptus fragrance keeps your pet’s piddle place smelling fresh and clean. The urine flows through the mat and into the container which is under the turf mat.

This product really does the trick to get the funk out of the false turf potty mat. It eliminates the odor of the turf, and works great. The product helps eliminate any odors left after clean up and clean the tray. Your dog uses the tray, after a week or so you empty and clean the tray. It is easy to use spray bottle.

Why We Like This:
  • Great solution for condo / apt living
  • Works great on the grass to keep it fresh
  • New and hot release

Best For cleanup: Natures Miracle Natural Enzyme Spray

Natures Miracle Natural Enzyme Spray
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Next on the list, we've got yet another spray that manages to win our hearts. It's the natures miracle natural enzyme spray and it's widely considered as spray that has the most suitable features. Nature's Miracle stain and odor remover's enzymatic formula works to eliminate stains and odors caused by puppies and dogs, including urine and feces accidents, food, drooling, bedding stain and odors and other hard to get out dog messes. It is designed to remove stains and odor caused by biomatter.

This stuff clears out any bio-enzymatic odors. The scent is very mild when applying and washes out. If you want total odor removal it can take up to 24 hrs of soaking and drying for the odor to be totally eliminated. It is also effective on stinky bra strap bands.

Why We Like This:
  • Cleans dog and cat pee and poop from surfaces
  • Best carpet cleaner for cleaning up doggie accidents
  • Works very well at removing cat urine odor
  • Works well on vomit, urine or feces