The 10 Best Night Guard Cleaning solutions (2023 reviews)

We consider a night guard cleaning solution to be a worthy investment in the long run. We are here to help you choose the right one for your needs from all the best available products in market today.

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Our Top Picks:

Best Overall: Buy: Retainer Brite Night Guard Cleaning Solution READ REVIEW

Best For getting them: Buy: Polident Night Guard Cleaning Solution READ REVIEW

Best For brace: Buy: Efferdent Night Guard Cleaning Solution READ REVIEW

Best For maintenance: Buy: Breelex Night Guard Cleaning Solution READ REVIEW

Best With All major Dental Appliances: Buy: Dental duty Night Guard Cleaning Solution READ REVIEW

Best For multiple uses: Buy: Smartguard Night Guard Cleaning Solution READ REVIEW

Best With sleep apnea device: Buy: isonic Night Guard Cleaning Solution READ REVIEW

Best For Denture baths: Buy: M3 naturals Night Guard Cleaning Solution READ REVIEW

Best With Ultrasonic Cleaner: Buy: Blumway Night Guard Cleaning Solution READ REVIEW

Best For toilet: Buy: project Better Night Guard Cleaning Solution READ REVIEW

Best Overall: Retainer Brite Night Guard Cleaning Solution

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The retainer brite night guard cleaning solution is capable of outshining several other solution featured in this list in overall features. ANYONE THAT HAS A KID COMING OUT OF BRACES KNOWS THE RETAINER IS IMPORTANT AND THIS HELP KEEP THE RETAINER CLEAN. They may or may not be as powerful as the sanitizing tablets you use for hiking/camping when you won’t be near soap for a while, but for home use, they do a great job.

This cleans it well and is so easy. It is easy to use, clean after 15 minutes, and fresh flavor. The foil packaging keeps the tablets dry so they will effervesce upon being dropped into the water. It’s hard to just soak it for 15 minutes and remove. The scent is very medicinal but it is good value for the money.

• Easy to remove plaque and freshen breath
• Whitening affect and doesn't remove any stains
• Easy to use and keeps mouthpiece ckean

Best For getting them: Polident Night Guard Cleaning Solution

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We would, of course, be remiss if we didn't mention polident night guard cleaning solution for daily purpose. These Poloident proguard retainer cleaning effervescence tablets make keeping your retainers clean a snap. It foams and does its work. The tablets work well for cleaning mouth guards. There is no residual taste or smell on the mouth guard after it dries which is great. The Polident proguard retainer cleaning tablets are very easily dissolved in warm water, as long as soak in the water several minutes and brush it that can remove bacteria and remove the mouth guard odors.

This product really works and it’s so easy to use. It is suitable for use on most removable oral appliances. These are great to use on toothbrush heads too to help keep them clean as well. This product is a must have for anyone with a night guard or daily retainer.

• Perfect for mouth guards and retainers
• Easy to use, gets the job done
• Will take scale and crud off of a lot of things
• Great value for crystal clear cleaning

Best For brace: Efferdent Night Guard Cleaning Solution

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If you often find yourself scrambling for appropriate and satisfactory solution, efferdent night guard cleaning solution is your solution. Efferdent complete clean antibacterial cleaner tablets provide an everyday, odor-free clean. It is good for night guard maintenance. These are also great overall 'cleaning tablets' and can be used to clean your sink or your toilet as well. This product makes it feel SO clean. It will last a long time. It works for retainers too.

• Great for keeping retainers and night guards clean
• Cleans coffee cups and snoring mouth device
• Works great for cleaning & disinfecting night guards

Best For maintenance: Breelex Night Guard Cleaning Solution

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Breelex has been making great solution for years, thanks to a combination of clever design and appropriate materials. These little retainer cleaner tablets are the perfect thing. It is easy to use individual packets, dissolve quickly. It is perfectly removes any plaque or discoloration and doesn't leave any chemically aftertaste on the trays/retainers. The tablets dissolve quickly. It makes your device minty fresh. The retainer comes out clean and fresh smelling. It is great for daily cleaning and maintenance.

• Definitely clean and sanitized and no flavor left over
• Convenient, easy to use, good minty fresh, germ killing, cleaner
• Very easy to use, no strong taste and cleans well

Best With All major Dental Appliances: Dental duty Night Guard Cleaning Solution

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If you are searching for a satisfactory solution for your daily usage, you cannot go wrong with the dental duty night guard cleaning solution. It works with all major dental appliances. It is great for cleaning mouth guards. The cleanser is a tablet that is made of potassium persulfate compound, sodium perborate, sodium bicarbonate, etc, etc. It cleans very well and leaves you with crystal clear, or free retainers. It can be used on various dental appliances for cleaning and sanitizing.

The packaging makes it great for travel purposes. It is best cleaner for smile direct or invisalign. This cleared up a lot of fogginess and weird staining.

• Easy to use and very effective
• Experience an exhilarating burst of minty freshness to supercharge your morning
• Delivers what they promise

Best For multiple uses: Smartguard Night Guard Cleaning Solution

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The smartguard night guard cleaning solution is capable of outshining several other solution featured in this list in overall features in its price range. If effervescent cleansers have ruined your soft liner denture, this cleaner will be safe with antibacterial professional strength solution cleaner. The SmartGuard Premium Cleaner is safe to pour down the drain. It cleanses the braces beautiful, with almost no scrubbing and removes stains. It is made from a different material, than retainer.

The SmartGuard Premium Cleaner will kill bacteria and remove embarrassing odor from your oral appliance and leave a pleasant, subtle mint flavor. It can be used in a custom night guard.

• Each packet cleaning solution lasts 7-10 days
• Very practical and easy to use
• Absolutely essential for the users of the invisalign aligners

Best With sleep apnea device: isonic Night Guard Cleaning Solution

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The isonic night guard cleaning solution is suitable and reliable and fits well with your daily usage. It is the ultimate denture cleaning system for home use. It uses sound waves to penetrate into crevices and cavities to remove particulates from dentures, retainers, and mouth guards. The vibrations of the machine reach every crevice and indentation, and the dish detergent removes odor-causing bacteria. The cleaning process removes finest particles that permits a secure upper denture. It is great with no chemicals and no uv light.

The main ingredients are Potassium Peroxymonosulfate, Potassium Bisulfate. It has a rechargeable battery which makes it even more portable. It takes very little space unlike the jewelry ultrasonic cleaners.

• Fits full set of dentures and cleans them really well
• Makes dental hygiene so much easier
• New and hot release

Best For Denture baths: M3 naturals Night Guard Cleaning Solution

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If you want nothing less than best convenient solution, then m3 naturals night guard cleaning solution is the one you should definitely consider. Soaking daily in a denture bath is highly recommended and will provide you with the best results by preventing food particle, cloudy film, and plaque buildup. It cleans thoroughly and rinses completely and easily. It makes them clear and the flavor is minty fresh. It smells great and the packaging makes it easy to take on the road.

This is so easy to use, just pop the tablet in a glass and put your retainer in and the bubbles do the rest. They don’t leave any taste or color behind, and keep them looking clear and fresh. It cleans and removes odor, which is a great value per tablet.

• Excellent product for cleaning plastic invisalign and night retainers
• Makes the daily routine of cleaning either item so easy
• Cleaned trays well, easy to use, no residue
• Fresh smell and easy to clean

Best With Ultrasonic Cleaner: Blumway Night Guard Cleaning Solution

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Next on the list, we've got yet another solution that manages to win our hearts. It's the blumway night guard cleaning solution and it's widely considered as one of the best convenient solution you can buy. It is a high quality and high-cost performance denture cleaner for your choice. It is used for all kinds of denture, retainer, aligner, mouth guard, electric toothbrush replacement heads. The device shuts off after it is done and you know when it’s on and when it’s not because it hums and a noticeable hum. These are beginning to develop a film on them as well as some mild calcium buildup in the deep crevices.

The machine is very small, just pour the water, and wipe the container, It is very easy to clean and simple. It is gentle and removes all plaque buildup on the trays. There is a small port in the back where you plug in the round wire that is connected to an AC adapter. It helps clean your teeth with ease.

• Works wonderfully for clear plastic retainers
• One of the new comers and featured product

Best For toilet: project Better Night Guard Cleaning Solution

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For a low asking price, project better night guard cleaning solution has managed to overwhelm their customers by packing as many features as they could. These retainer cleaner tablets come packed in individually sealed, well labeled, foil packets with six to a sheet. They remove stains from coffee mugs, travel mugs, water bottles, tea cups and work for glasses bottles, jars, vases. It is also used for cleaning dentures.

This retainer cleaner works very well removing the build up. It is easy to use, cleanses well, leaves retainers feel fresh. It desolves quickly with a nice fuzzy minty smell. It is made for easy travel and also works well for retainer. These tables can be used to clean a lot of things, but they work well for dental devices.

• Good cleaning action with a pleasant (not overwhelming) mint scent
• Effective retainer cleaner and useful to clean water bottles
• Residue to scrub, no lingering odor of yuck at all