The 10 Best Prescription Allergy Pills (2023 reviews)

We consider a prescription allergy pill to be a worthy investment in the long run. We are here to help you choose the right one for your needs from all the best available products in market today.

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Our Top Picks:

Best Overall: Buy: Basic Care Prescription Allergy Pill READ REVIEW

Best For Non drowsy: Buy: Xyzal Prescription Allergy Pill READ REVIEW

Best For coughing: Buy: Zyrtec Allergy Medicine READ REVIEW

Best With Nasal decongestant: Buy: Zyrtec Prescription Allergy Pill READ REVIEW

Best For daytime: Buy: Claritin Prescription Allergy Pill READ REVIEW

Best For rash: Buy: Healthcareaisle Prescription Allergy Pill READ REVIEW

Best For chronic sinusitis: Buy: Valumeds Prescription Allergy Pill READ REVIEW

Best For Allergy sufferer: Buy: Basic Care Allergy Medicine READ REVIEW

Best For dog: Buy: Healthcareaisle One Tablet READ REVIEW

Best For run: Buy: Xyzal Hour Relief READ REVIEW

Best Overall: Basic Care Prescription Allergy Pill

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The latest basic care prescription allergy pill is an absolute beast in terms of its features, and rightfully takes the top spot with ease. Being someone who suffers from year long allergies, this medicine is a lifesaver. Cetirizine is a second-generation antihistamine designed for once-daily use. It provides relief of symptoms due to hay fever or other upper respiratory allergies. This product resolves all of the symptoms and does it very quickly. It works exactly as it should at a mere 1/100th the cost of the name brand stuff for the quantity you get.

These gel capsules are pretty small and easy to swallow. It's nice to not sound stuffed up all of the time and blow through a package of tissues daily. The tablets are quite small and oval shaped. It is not as much "medicine head" side effects like you get with some anti-histamines either.

• Helps breath easy with allergy season in full swing again
• Works fast and is very effective
• Good brand reputation

Best For Non drowsy: Xyzal Prescription Allergy Pill

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The xyzal prescription allergy pill might be a relatively new release, but it's still nothing short of impressive this year, thanks to multiple price cuts and added new features over the past few months. This particular allergy medicine is designed to work while you sleep. It provides 24 hour symptom relief after just one day. These small pills are the perfect solution to a problem that can sometimes last for several weeksthey actually shorten that time a great deal. It works during the toughest of seasonal allergy days. It's great for minimizing allergies.

These are the best products to stop the sniffles. This product is a great remedy for allergy.

• Works great for itching allergies where others do not
• Very small pill, easy to swallow
• Works well for allergies, but very overdone and wasteful packaging
• Keep bronchitis and sinus infections from happening

Best For coughing: Zyrtec Allergy Medicine

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We would, of course, be remiss if we didn't mention zyrtec allergy medicine for daily purpose. This 24 hour allergy relief medicine starts working at hour 1 and works twice as hard when you take it again the next day, and is suitable for those ages 6 and older. It helps with seasonal allergies, dust, pets (to an extent), hives, etc. It works every time without fail, in 10 minutes and lasts for the entire day. Taking them at night help combat the sleepiness that sometimes onsets in the beginning, and they last the full 24 hours.

This is the only brand that helps reduce allergy symptoms without causing drowsiness. They're made of the same ingredients like ones in stores. It takes care of it right away. It is great espresso for the pill count.

• Good investment for long term
• New and hot release

Best With Nasal decongestant: Zyrtec Prescription Allergy Pill

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We know from years of feedback from readers, customers and amazon sellers, what most people want in a convenient and appropriate pill. The zyrtec prescription allergy pill is exactly that - it's a simple pill that hits all the right notes. These are 'life savers' when you have a big day ahead at work. These prescription-strength allergy medicine work fast and stay strong by providing all-day allergy relief that starts working hard at one hour and works twice as hard when taken again the next day. It really helps those who have sinusitis, keeps your throat and clear for at least 3 days. It is suitable for those ages 6 and older.

The pills are very small which makes them easy to swallow and they truly last 24 hours, sometimes more. It is easy to swallow and they truly last 24 hours, sometimes more. The allergy medicine provides powerful, effective relief for a full 24 hours in just a single dose. It is good for light to medium pollen days.

• A must try for allergies sufferers
• One of the new comers and featured product

Best For daytime: Claritin Prescription Allergy Pill

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The claritin prescription allergy pill should be able to handle its purpose and duties with ease. Claritin tablets and claritin liqui-gels both contain loratadine, a powerful antihistamine that helps to block the histamines that your body produces in response to allergens. It provides relief of symptoms triggered by over 200 different allergens from pets, pollen, dust and mold. The Claritin liqui-gels, on the other hand, are liquid-filled capsules that are also easy to swallow, and provide you with the same.

This pack comes with some clear liqui gels as well. It contains 10 mg of loratadine per tablet or capsule. They work well in providing relief and it lasts a long time as well. It works fine especially good for watery eyes. It is also the only truly non-drowsy solution out there.

• Good bundle of tablet and liquid gel forms
• Drowsy allergy relief in a convenient package
• Hour, non-drowsy indoor and outdoor allergy relief

Best For rash: Healthcareaisle Prescription Allergy Pill

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We know from years of feedback from readers, customers and amazon sellers, what most people want in a convenient and appropriate pill. The healthcareaisle prescription allergy pill is exactly that - it's a simple pill that hits all the right notes. Fexofenadine tablets provide 24 hours of allergy relief. This is a second generation of antihistamines. It has the same active ingredient as allegra allergy 24 hour tablets. It is a good substitute for the prescribed fexofenadine. This magic pill takes care of it all. It is a non-drowsy allergy medicine that provides effective relief from indoor and outdoor allergies.

• Non drowsy and only take one dose per day
• More sneezing, sniffling, rashes, hives, difficulty breathing, runny noses, dry/watery/itchy eyes
• One of the new comers and featured product

Best For chronic sinusitis: Valumeds Prescription Allergy Pill

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We know from years of feedback from readers, customers and amazon sellers, what most people want in a convenient and appropriate pill. The valumeds prescription allergy pill is exactly that - it's a simple pill that hits all the right notes. Valumeds allergy medicine can help relieve symptoms around the clock to give you clarity no matter where your travels take you. They work without spending a ton on brand name meds. These are excellent for someone who has a hard time swallowing big pulls or if you are someone that takes a lot of meds because they are so tiny and the med works well.

This medicine works great and is very very inexpensive compared to name brands and even generic drug store brands. The bottle is recyclable unlike those blister packs which pills are sold in. They do not make you sleepy. As someone who has pretty bad seasonal allergies, this product definitely gives you the best bang for your buck. It is great value for money to subscribe and save with 15% off.

• Working well for seasonal allergies, good substitute for name brand
• Highly competitive and comparable generic form of zertec
• Great value and well worth the try for your allergies

Best For Allergy sufferer: Basic Care Allergy Medicine

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The basic care allergy medicine's superior materials makes sure that it ages well with use. This histamine blocker temporarily relieves symptoms due to hay fever or other upper respiratory allergies. When taken as directed, this allergy medicine will help your runny nose and other common allergy symptoms without making you feel drowsy. It is loratadine 10 mg, a powerful antihistamine in original prescription strength that is tough on allergies while it provides multi-symptom relief. It is great value for money-you get 400 tabs in each bottle.

The top is child proof but not hard to open and close. This is easy to take because it's just a little white pill that's easy to swallow. It is good for seasonal allergies that have respiratory symptoms.

• Economical (generic - loratadine) to claritin
• Small tablets make for easy swallowing
• Lactose monohydrate, magnesium stearate, providone pregelatinized starch

Best For dog: Healthcareaisle One Tablet

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Next on the list, we've got yet another pill that manages to win our hearts. It's the healthcareaisle one tablet and it's widely considered as pill that has the most suitable features. Cetirizine tablets provide 24 hours of allergy relief. Each original prescription strength antihistamine tablet provides 24 hours of relief from indoor and outdoor allergies. It is good value for 300 tablets with recommended dosage of one tablet per day. The Cetirizine Hydrochloride provides 24 hours of relief from indoor and outdoor allergies.

• Excellent generic alternative to expressive zyrtec
• Save money and no sneezing too
• Helped during the academy season with the nasal congestion and coughing

Best For run: Xyzal Hour Relief

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Not everyone likes to purchase pill for their daily purpose, but the xyzal hour relief would be an anomoly. If you have to drive on the following day, or do anything critical and demanding, this one WILL make you sleepy and not fit to drive again. It helps with the stuffy nose and itchy eyes. It can actually double as a sleep aid making you feel refreshed and blissful in the morning. It helps with both indoor and outdoor allergens. It works well if you are on cardiac meds. It provides continuous allergy relief that is just as effective at hour 24 as it is at hour.

• The best 24 hour allergy medication over the counter
• Good brand reputation