The 7 Best Systane Overnight Gel Drops (2023 reviews)

systane overnight gel drops
We consider a systane overnight gel drop to be a worthy investment in the long run. We are here to help you choose the right one for your purposes from all the best available products in market today.

Our review process:

Our Top Picks:

Best Overall:
Buy: Systane Best Eye Lubricant

Best For day:
Buy: Systane anytime Protection

Best For Comfort:
Buy: Systane Eye Lubricant

Best With No side effects:
Buy: Systane Gel formula

Best For Eye infection:
Buy: Systane Nighttime Protection

Best Ointment:
Buy: Systane Best Overnight Eye Gel

Best For Nighttime Eye:
Buy: Systane Overnight Gel Drop

Best Overall: Systane Best Eye Lubricant

Systane Best Eye Lubricant
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The systane best eye lubricant should be able to handle its purpose and duties with ease. The Systane Nighttime Lubricant Eye Ointment is great for people suffering with chronic dry eyes. It is dry and this stuff is fantastic. It’s heavy duty. It works well for dry eyes during the day and especially at night. It is very effective for all night eye lubrication. It is an excellent gel, which keeps you from waking up with dry eyes. These drops are very, very thick. It is inclined to fall out and/or cause physical irritation.

Why We Like This:
  • Lasts a long time, into the next day
  • Wonderful product for nighttime dry eye relief
  • You can avoid contamination by never touching the eye with the tube

Best For day: Systane anytime Protection

Systane anytime Protection
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The systane anytime protection's material feels more premium than its price would suggest. This stuff is like a vinaigrette salad dressing. It works well for severe dry eye. It goes in goey and blurry, and you close your eyes for a few minutes in order to let it penetrate your eyeball surface. It is good as there are high performance drops.

The gel formula is top notch. It is designed for severe dry eye. These are not very good to use during the day because they make your vision because they are thicker than regular eyedrops.

Why We Like This:
  • Very thick clouds vision makes it hard to drop in the eyes
  • Lot of satisfied buyers

Best For Comfort: Systane Eye Lubricant

Systane Eye Lubricant
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The systane eye lubricant has killer features for the price point. This eye ointment is the best over the counter Eye ointment you can buy. It works great if you can get it into your eye and are okay with a little blur to your vision. This makes your eyes comfortable. It is very soothing to the eye. This ointment stays most all day without having to add throughout the day. It is perfect for chronic dry eye. If you have severe dry eyes this ointment is a must use product for nights.

Why We Like This:
  • Great stuff for dry eye disease
  • More issues with dry or watery eyes
  • Great for dry eyes at night

Best With No side effects: Systane Gel formula

Systane Gel formula
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Compared with other products by Systane, the systane gel formula has a convenient design. This gel is great for night time. Their thick, gel formula creates a protective shield over your eyes, forming a barrier against irritating dry air and debris. It only takes one small drop in each eye and takes a few minutes to absorb. The gel formula works longer and better when treating Dry Eye irritation in low humidity climates.

It has to be shaken first, and the drops come out easier after that. It is easy to slip into even a small purse or pocket.

Why We Like This:
  • Relieves symptoms of itching, burning eyes
  • Gives several hours of protection of dry eye disease
  • Perfect for dry eyes during the night

Best For Eye infection: Systane Nighttime Protection

Systane Nighttime Protection
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Compared with other products by Systane, the systane nighttime protection has a convenient design. Systane gel drops and systane gel contain different active ingredients. They are both manufactured by Alcon, and contain the exact same active ingredients, as well as the exact same inactive ingredients, all in the exact same order. This gel works throughout the entire night and Systane Ultra eye-drops in the morning removes any remaining blurred vision. This is a thick fluid that stays on the eye for most or all of the night, is comfortable, and you can still see within a minute or so of putting it on.

The gel is pretty thick, and will initially make your vision pretty blurry, but it works great for dry eyes. They come in a tube which makes it impossible to get just one or two drops into your eyes. The gel is thicker and lasts longer, and does a better job. The gel is thicker and lasts longer, so it won't dry out or leave any residue in your eye or your contacts.

Why We Like This:
  • Works great for dry at night
  • Great product to keep your eyes healthy
  • Lot of satisfied buyers

Best Ointment: Systane Best Overnight Eye Gel

Systane Best Overnight Eye Gel
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Systane makes beautiful and great drop with classic and smartly choosen materials. If you're the type that has "wet" eyes but actually dry eyes this is for you. This particular item is an ointment that is almost like thick Vaseline Ointment that you put in the sac below your lower lid. It provides dry eye symptom relief at night. It does get on your eye lashes over time but the comfort it provides is well worth it.

This product is good for night time usage, it is preservative free and it helps lubricate dry eyes. The long narrow tip makes it easy to apply. It provides cushion for hours. It is for use as a lubricant to prevent further irritation or to relieve dryness of the eye. The ointment really works to protect the eye.

Why We Like This:
  • Great relief for severe dry eyes
  • Cooling and relieving to use at bedtime
  • Good investment for long term

Best For Nighttime Eye: Systane Overnight Gel Drop

Systane Overnight Gel Drop
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Systane makes beautiful and great drop with classic and smartly choosen materials. Whether you need dry eye relief or simply want to support healthy vision, Systane has a product that’s right for you. This is a mineral oil ointment. It moistens eyes to get you through the night comfortably. If you have dry eyes, this is the best, thickest, most protective, most moisturizing, longest lasting, etc. It protects and soothes the eyes very nicely all night with no pasty wake up residue. This works very well for severe dry eye at night. It stays in the eye for a long time. This is a wonderful product for night-time use by people with severe dry eye.

Why We Like This:
  • More scratchy, irritated, painful eye issues
  • Great if you sleep with your eyes slightly open
  • Eye scrub and zaditor allergy drops as well as a heat mask