The 12 Best Otc Antihistamines (2022 reviews)

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Are you looking for collection of best otc antihistamines ? Your search ends here.

Our review process:

Our Top Picks:

Best Overall:
Buy: Claritin Otc Antihistamine
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Best For Runny Nose:
Buy: Benadryl Otc Antihistamine
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Best With Excellent Price:
Buy: Amazon Basic Care Otc Antihistamine
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Best For Affordable Price:
Buy: Good Sense Otc Antihistamine
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Best With Excellent Price:
Buy: Valumeds Otc Antihistamine
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Best With Excellent Price:
Buy: Gencare Generic Healthcare Otc Antihistamine
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Best For Bad Allergy:
Buy: Major Pharmaceuticals Otc Antihistamine
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Best For Bad Allergy:
Buy: Nasal Crom Otc Antihistamine
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Best For Runny Nose:
Buy: Rite Aid Otc Antihistamine
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Best For Adult:
Buy: Xyzal Otc Antihistamine
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Best For Great Price:
Buy: Geri-Dryl Otc For Benadryl Ultratabs Otc Antihistamine
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Best With Excellent Price:
Buy: Rugby Laboratories Otc Antihistamine
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Best Overall: Claritin Otc Antihistamine

Claritin Otc Antihistamine
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Claritin OTC antihistamine is the epitome of what a great antihistamine should be. The claritin OTC antihistamine comes with an expiration date, helps with allergies and it is ahead of the estimated date. One tablet contains 10 mg of loratadine. Moreover, this is simple and it is best for small pills.

The antihistamine is made with no artificial colors, claritin reditabs provides non-drowsy allergy relief from pollen, dust mites, pet dander, and mold and from symptoms like sneezing, runny nose, itchy/watery eyes, and itchy nose or throat. Most importantly, the claritin OTC antihistamine is the #1 doctor recommend non-drowsy oral allergy brand.

Most buyers agree that the antihistamine has worked well over the six months of its use. In addition, they say that the antihistamine is something you would have to google.

Top Customer Quotes:
  • The doctor recommended the non-drowsy oral allergy brand.
  • One small, non-drowsy claritin tablet effectively relieves allergy symptoms all day.
  • This is an antihistamine, so it hinders the cascade triggered by allergens.
  • This does start to work immediately, but not as quick as you think.

Best For Runny Nose: Benadryl Otc Antihistamine

Benadryl Otc Antihistamine
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If you often find yourself confused about convenient and suitable antihistamine, benadryl OTC antihistamine should be your first option for buying. The benadryl OTC antihistamine works well for scratchy throat, its price is excellent and it is with fast shipping. Works when you need it most with allergy medicine in small, convenient antihistamine tablets that put your allergies to rest. Further, this is perfect for itchy skin and it is great for emergency use.

The antihistamine can live with especially in children and it helps with allergies. Further, it can be used by adults and children ages six and up for relief of both indoor and outdoor allergies. Lastly, the benadryl OTC antihistamine is best for fast acting, is best for allergic reactions and it is made with titanium dioxide.

Almost all buyers opine that the antihistamine is great for breathing when sleeping. And, a few say that the antihistamine is great to have on hand for unexpected reactions. And, a few also found that the antihistamine is easy to swallow and is good value. In conclusion, at the price, they believe that they got a steal of a deal with it.

Top Customer Quotes:
  • This means no headaches, and it works really well.
  • I can not complain it works well for what it is.
  • This comes with 100 and it's actual benadryl not a generic.
  • This is a bottle with individual tablets.

Best With Excellent Price: Amazon Basic Care Otc Antihistamine

Amazon Basic Care Otc Antihistamine
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If you often find yourself scrambling for a convenient and suitable antihistamine, Amazon basic care OTC antihistamine should be your first option for buying. The amazon basic care OTC antihistamine is great as an alternative to zyrtec, is made with quick ship and it works fast. Treat yourself to all day allergy relief with Amazon basic care all day allergies. These allergy pills are an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms.

The antihistamine is made for large sizes and it is good for animal dander. Above all, the Amazon basic care OTC antihistamine works for a full 24 hours.

Almost all customers quickly discovered that the antihistamine is a once every 24 hour medication. Also, a few say that the antihistamine is like taking a dose of liquid cough syrup but like a 2-6 hour window. Moreover, a few strongly agree that these are gel cap style pills. Consequently, buyers were very happy to recommend it to friends and would-be buyers.

Top Customer Quotes:
  • This works for nasal congestion and is also best for allergy season.
  • This comes with an expiration date, is very effective and it is great for fast delivery.
  • This can cause tremendous itching when you try and stop taking it.
  • This is designed for once-daily use.

Best For Affordable Price: Good Sense Otc Antihistamine

Good Sense Otc Antihistamine
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Compared with other antihistamines in this category, the good sense OTC antihistamine has a convenient design. The good sense OTC antihistamine works well for good quality, works fine and it has features for a lower price. See product images above for full product details. These allergy pills are an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms.

The antihistamine is simple and it works for large size. Finally, the good sense OTC antihistamine is great for tree pollen, is great for tiny pills and it is best for fast acting.

Almost all customers agree that the antihistamine is great, especially for a whole year 's supply. Furthermore, a few also found that the antihistamine is used only the brand name pills, then found Walmart brand which is pretty good too and at an affordable price. In addition, a few say that these liquid gel capsules are clear with a 10 imprinted on them. In conclusion, at the price, they believe that they got a steal of a deal with it.

Top Customer Quotes:
  • This provides relief of symptoms due to hay fever or other upper respiratory allergies.
  • This has no taste really and is a great value for a year 's supply.
  • This is a sensitivity to a substance that is normally harmless.
  • This is a package of 25 once daily liquid gel capsules.

Best With Excellent Price: Valumeds Otc Antihistamine

Valumeds Otc Antihistamine
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Next on the list, we've got yet another antihistamine that manages to win our hearts. It's the valumeds OTC antihistamine and it's widely considered as one of the most convenient antihistamines you can buy. The valumeds OTC antihistamine works well for sore throat and it is great for a reasonable price. The manufacturer says: A powerful antihistamine, our formula helps control coughs and runny noses for clearer, healthier breathing. This anti - allergy medicine for kids and adults also helps reduce sneezing and itchy noses and throats.

The antihistamine is made with good service, is gluten-free and it works great for allergic. Finally, the valumeds OTC antihistamine is made for children under 6 years, is very cost - effective and it is made with titanium dioxide.

Most buyers agree that the antihistamine is the best price because other local department store sells 365 tabs for 8.97. And, a few also found that the antihistamine is great as a sleep aid as needed. Moreover, a few also found that this is diphenhydramine, which is the same antihistamine that is used in benadryl and other commercial brands but offered at a fraction of the cost.

Top Customer Quotes:
  • This is a terrific value for the number of pills.
  • This is used for pets some of the time, unlees highpolee.
  • This is great for alleviating the symptoms of stuffiness/runny nose.
  • This is great for children over 12 years, is beneficial and its price is right.

Best With Excellent Price: Gencare Generic Healthcare Otc Antihistamine

Gencare Generic Healthcare Otc Antihistamine
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If you want nothing but the best reliable antihistamine, then gencare generic healthcare OTC antihistamine is the one you should definitely consider. The gencare generic healthcare OTC antihistamine allows for great quality and it is great for allergies. Enjoy non - drowsy allergy relief that lasts for a full day. Moreover, the antihistamine comes with an expiration date, is great for red eyes and it will for excellent value.

Finally, the gencare generic healthcare OTC antihistamine is a powerful antihistamine that helps relieve and prevent itchy watery eyes, runny nose, congestion and an irritated itchy throat.

Almost all customers agree that the antihistamine works well without extra ingredients. In addition, they say that the antihistamine is a different formulation with a whole bunch of additional inert ingredients. In addition, a few strongly agree that the antihistamine is as good as the name brand but without the marketing and price of the original.

Why We Like This:
  • You don't have to suffer through indoor or outdoor allergies anymore.
  • It is small and easy to swallow for adults and children ages 6 and up.
  • Join thousands of satisfied allergies relief customers...click add-to-cart today.
  • This works for sinus issues, provides you with exceptional value and it works quickly.

Best For Bad Allergy: Major Pharmaceuticals Otc Antihistamine

Major Pharmaceuticals Otc Antihistamine
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The major pharmaceutical OTC antihistamines should be able to handle their purposes and duties with ease. The major pharmaceutical OTC antihistamines packaged well, are best for puffy eyes and it saves a lot. It works by blocking histamine, a certain natural substance that the body makes during an allergic reaction. Moreover, the antihistamine comes with an expiration date and it is easier to swallow.

Lastly, the major pharmaceutical, OTC antihistamine, comes with great stuff and it is designed for emergency use.

Most buyers quickly discovered that the antihistamine is good for human allergies too. And, a few strongly agree that the antihistamine does not sedate and it does not raise blood pressure. And, they say that the antihistamine is a strong antihistamine, follow low end veterinary dose for cats. In conclusion, many buyers have used the antihistamine for more than a few months without any issues, and it shows no sign of giving up.

Top Customer Quotes:
  • These take effect quickly. Additionally, it is time to change meds.
  • This can be used on pets per vet.
  • This has allergies or if they tend to chew their feet or bodies.
  • This is OK. People use it for celiac rash, see below.

Best For Bad Allergy: Nasal Crom Otc Antihistamine

Nasal Crom Otc Antihistamine
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The nasal crom OTC antihistamine is capable of outshining several other antihistamines featured in this list in overall features in its price range. The nasal crom OTC antihistamine comes in at full strength, is very effective and it works fast. When mast cells erupt, they release histamines and other irritants that cause you to experience allergy symptoms such as a runny nose or sneezing. This nasal spray temporarily prevents and relieves nasal allergy symptoms including running / itchy nose, sneezing and allergic stuffy nose.

The antihistamine is beneficial and it buys more. Lastly, the nasal crom OTC antihistamine twice daily and it is complete.

Most customers opine that the antihistamine is a proven medical treatment for nasal allergies. Also, a few say that the antihistamine is great for relieving allergy symptoms quickly. And, they strongly agree that the antihistamine does help to illiminate allergies. Overall, most buyers agree that the antihistamine suits best, and no one questions it.

Top Customer Quotes:
  • This works for controlling hayfever symptoms.
  • No drowsiness or jitters, plus it is non - habit - forming.
  • This works in advance of congestion, not a decongestant.
  • This can be used in conjunction with these medicines.

Best For Runny Nose: Rite Aid Otc Antihistamine

Rite Aid Otc Antihistamine
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The rite aid OTC antihistamine is the most suitable antihistamine on the market today. The rite aid OTC antihistamine is for children 12 years, works well for good quality and it works fast. You will love this allergy medicine calms hay fever or other respiratory allergies. These chlorpheniramine maleate 4mg + phenylephrine hci 10mg tablets provide natural allergy relief and relieve congestion due to the common cold, respiratory allergies and hay fever for adults and children ages 12 and older.

The antihistamine is great for children under 12 years, works well for a low price and it is great for a reasonable price. Further, the antihistamine is simple and it has the same ingredients. Most importantly, the rite aid OTC antihistamine is great for tree pollen and it is great for sore throat.

Most buyers found that the antihistamine is a great medicine for allergy season. Further, they strongly agree that the antihistamine can be taken every four hrs. Further, a few strongly agree that the antihistamine can act as a sleep aid too. Overall, for most buyers, the antihistamine was best suited.

Top Customer Quotes:
  • Allergies don’t stand a chance against rite aid’s allergy and cold medicine for adults.
  • Lot of satisfied buyers.

Best For Adult: Xyzal Otc Antihistamine

Xyzal Otc Antihistamine
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Xyzal has been making great antihistamines for years, thanks to a combination of clever design and appropriate materials. The xyzal OTC antihistamine works better than claritin and it is coated with titanium dioxide. Xyzal starts working in one hour, so you start feeling better faster. And, this provides continuous allergy relief that is just as effective at hour 24 as it is at hour 1.

The antihistamine is a prescription strength allergy medicine that relieves symptoms of indoor and outdoor allergies, including sneezing. Further, the antihistamine relieves allergies symptoms, is better than zyrtec and it is very safe. Finally, the xyzal OTC antihistamine is good for itchy ears and it is better than claritin.

Almost all customers quickly discovered that the antihistamine is a happy medium between the two. Also, they strongly agree that the antihistamine has zero side effects. Additionally, it is easy to swallow with water. Moreover, a few strongly agree that the directions recommend taking a pill once every 24 hours, preferably before bed. In short, for almost all buyers, Xyzal product was what they were looking for.

Why We Like This:
  • Xyzal gives you rapid relief from allergy symptoms, including sneezing.
  • Maximum strength relief: xyzal is full prescription strength available without a prescription.
  • This is best for itchy skin and it helps with allergies.
  • Simply put, the more severe your symptoms, the more your sleep may be affected.

Best For Great Price: Geri-Dryl Otc For Benadryl Ultratabs Otc Antihistamine

Geri-Dryl Otc For Benadryl Ultratabs Otc Antihistamine
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The features department is where geri-dryl OTC for benadryl ultratabs OTC antihistamine truly manages to shine. Best part: geri-dryl OTC for benadryl ultratabs OTC antihistamine costs comparatively low and it is available to ship in 24 hours. Moreover, the antihistamine has the same ingredients and it works as expected. To sum up, with a 4.6 rating and more than 1808 buyers, the geri-dryl OTC for benadryl ultratabs OTC antihistamine stands as the best choice.

Almost all customers agree that the antihistamine is good as name brand benadryl. And, a few also found that the antihistamine is perfectly for a great price. Without any doubt, this product passed the test and had very satisfied buyers eager to share their experience.

Why We Like This:
  • Lot of satisfied buyers.
  • One of the newcomers and featured product.

Best With Excellent Price: Rugby Laboratories Otc Antihistamine

Rugby Laboratories Otc Antihistamine
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The rugby laboratories OTC antihistamine is capable of outshining several other antihistamines featured in this list in overall features for the price point. The rugby laboratories OTC antihistamine is used for allergic conditions. It works by blocking histamine, a certain natural substance that the body makes during an allergic reaction. And, it can be trusted for good quality and it is good for minor allergies.

The antihistamine can with fast service and it works fine. Also, the antihistamine is very cost - effective and it is great for summer hayfever. Lastly, the rugby laboratories OTC antihistamine works as expected, is made for children under 6 years and it is great with an excellent price.

One customer says - "A penny a tablet is certainly the right price, and yes it helping. ". Most buyers opine that the antihistamine is great for the post nasal drip.

Why We Like This:
  • This is with fast shipping and it has stopped the itching.
  • Chlorpheniramine relieves: sneezing, itchy, watery eyes, itchy throat, runny nose.
  • Good brand reputation.